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ANTI CANCER DRUGS

1)Alkylating agents

Busalfan

Carmustine

Lomustine

Semustine

Chlorambucil

Cyclophosphamide

Melphalan

Dacarbazine

Mechlorethamine

Ifosfamide

Thiotepa

Temozolomide

Streptozocin

Estramustine

2)Anti metabolites

A)Folic acid analogues

Methotrexate

B)Purine analogues

Thioguanine

Mercaptopurine

Fludarabine

Pentostatin

Cladribine

C)Pyrimidine analogues

Cytarabine

Fluorouracil

Floxuridine

Gemcitabine

Capecitabine

3)Antibiotics

Bleomycin

Dactinomycin (actinomycin- D)

Mitomycin

Daunorobucin

Idarabicin

Doxorubicin

Pilcamycin

Mitoxantrone

4)Natural products

A)Vinca alkaloids

Vincristine

Vinblastine

Vinorelbine

B)Epipodophyllotoxins

Etoposide

Teniposide

C)Camptothecins

Topotecam

Irinotecam

D)Taxanes

Paclitaxel

Docetaxel

E)Enzymes

L- Asparaginase

5)Miscellaneous drugs

Hydroxyurea

Cisplatin

Carboplatin

Oxaliplatin

Procarbazine

Hexa methyl melamine

Altretamine

Arsenic trioxide

Tretinoin

Bexarotene

Deneleukin

Thalidomide

6)Protein tyrosine kinase inhibitors

Imatinib

7)Epidermal growth factor receptor inhibition

Gefitinib (Iressa)

Erlotinib

8)Protiosome inhibitor

Bortezomib

9)Hormones and antagonists

A)Somatostatin analogs

Octreotide (sando statin)

B)Gonado tropin releasing hormone (Gn RH) agonists

Goserelin

Buserelin

Leuprolide

C)Gonado tropin releasing hormone (Gn RH) antagonists

Cetrorelix

Ganirelix

Abarelix

D)Corticosteroids

Dexamethasone

Prednisolone

E)Adrenocortical suppressants

Aminoglutethimide

Trilostastin

F)Aromatase inhibitors

Anastrozole

Letrozole

Exemestane

G)Estrogen receptor antagonists

Tamoxifen

Toremifen

Fulvestrant

H)Androgen receptor blockers

Flutamide

Bicalutamide

Nilutamide

I)Progestins

Hydroxyl progesterone

Medroxy progesterone

Megestrol acetate

J)Estrogens

Diethyl stilbestrol

Ethinyl estradiol

K)Androgens

Testosterone propionate

Fluoxy mesterone

10)   Monoclonal antibodies

A)Naked MAb’s

Rituximab

Alemtuzumab

Trastazumab

Cetuximab

Bevacizumab

B)MAb’s cytotoxic conjugates

Gemtuzumab

Ozogamicin

C)Radio isotope based MAb’s

Ibritumomab-Y

Yyttrium

Tostitumomab-I131

11)   Protectants

A)Colony stimulating factor (CSF)

Filgrastim

Sargramostim

B)Thiophosphate cytoprotectants

Amifostine

C)Acrolein conjugator

Mesna

D)Iron chelator

Dexrazoxane

E)Thrombopoitic growth factor

Oprelvekin

Thrombopoeitin

F)Others

Leramisole

 

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